Application

PRODUCT NAME	:	ETHYLACETOACETATE
CAS number	:	141-97-9
UN number	:
Formula	:	CH3COCH2COOC2H5
Odour	:	FRUITY
Solubility in water	:	SOLUBLE
Density	:	1.025 at 20 ^oC
Boiling point	:	180^oC
Melting point	:	-39 ^oC
Viscosity	:
Flashpoint	:	85 ^oC
Explosive limits	:
Vapour pressure	:	0.8 mbar at 20^oC
Skin absorption/irritation	:	YES
TLV Country	:
Pollution category 1994	:	(D)

Dosage

MSDS

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Product Name	ETHYL ACETO ACETATE
Part Number	RXSOL-19-1169-210

Company Details:

RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA

Branch : Kandla, Mumbai , Chennai, Vizag, Kolkata, UAE , OMAN , CANADA and KENYA

Phone	+91 22 20871200 - 1400
Fax	+91 22 27612100 :::AOH :0091 9821214367
Email	mail @ rxmarine.com
Website	www.rxmraine.comA

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Chemical Name	CAS	EC number	Weight	Formula
Acetoacetic ester	141-97-9	205-516-1	<= 100 %	C₆H₁₀O₃

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Signal Word	None
Hazard Statements	H300 + H310 + H330 Fatal if swallowed, in contact with skin or if inhaled. H314 Causes severe skin burns and eye damage. H400 Very toxic to aquatic life.
Precautionary statements	P260 Do not breathe dust. P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Classification of the substance or mixture	Not a hazardous substance or mixture according to Regulation (EC) No 1272/2008.
Supplemental Hazard Statements	EUH032 Contact with acids liberates very toxic gas.
Other hazards	This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

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General advice	None
If inhaled	After inhalation: fresh air.
Eye Contact	After eye contact: rinse out with plenty of water. Remove contact lenses.
Swallowed	After swallowing: make victim drink water (two glasses at most). Consult doctor if feeling unwell.
Skin Contact	In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.
Inhalation	Remove patient to fresh air, keep warm and at rest and get medical assistance in necessary.
Ingestion	Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
Most important symptoms and effects, both acute and delaye	The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
Indication of any immediate medical attention and special treatment needed	No data available

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Flammability	Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Suitable extinguishing media	Water Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media	For this substance/mixture no limitations of extinguishing agents are given.
Special hazards arising from the substance or mixture	Carbon oxides Combustible. Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating. Development of hazardous combustion gases or vapours possible in the event of fire.
Further information	Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.
Hazardous combustion products	Fire may cause the evolution of Sulphur oxides, nitrogen oxides.
Advice for firefighters	In the event of fire, wear self-contained breathing apparatus.
Protective Equipment	Use personal protective equipment.
Specific Hazards Arising from the Chemical	Oxides of phosphorus Sodium oxides Not combustible. Fire may cause evolution of: Oxides of phosphorus Ambient fire may liberate hazardous vapours.

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Personal precautions, protective equipment and emergency procedures	Advice for non-emergency personnel: Do not breathe vapors, aerosols. Keep away from heat and sources of ignition. Evacuate the danger area, observe emergency procedures, consult an expert. For personal protection see section 8.
Spillage	Oxidizing material. Stop leak if without risk. Avoid contact with a combustible material (wood, paper, oil, clothing...). Keep substance damp using water spray. Do not touch spilled material. Prevent entry into sewers, basements or confined areas dike if needed. Eliminate all ignition sources. Call for assistance on disposal.
Enviromental Precaution	Do not let product enter drains.
Methods and materials for containment and cleaning	Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent and neutralising material (e.g. Chemizorb® H⁺, Merck Art. No. 101595). Dispose of properly. Clean up affected area.

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Advice on protection against fire and explosion	Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Incompatible materials	Keep away from alkalis, strong oxidizing agents and metals. Provide containment walls of adequate capacity to hold any accidental spills.
Hygiene measures	Change contaminated clothing. Wash hands after working with substance. For precautions see section 2.2.
Precautions for safe handling	For precautions see section 2.2.
Storage conditions	Tightly closed.
Storage class	Storage class (TRGS 510): 10: Combustible liquids
Specific end use(s)	Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
Advice on general occupational hygiene	Advice on safe handling Observe label precautions. Change contaminated clothing. Wash hands after working with substance.
Requirements for storage	Keep in cool and store under shade.

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Exposure controls	Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Control parameters	Ingredients with workplace control parameters Contains no substances with occupational exposure limit values.
Engineering Control	Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Eye/face protection	Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Body Protection	Protective clothing
Skin protection	This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de). Full contact Material: butyl-rubber Minimum layer thickness: 0,7 mm Break through time: 480 min Material tested:Butoject® (KCL 898) This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de). Splash contact Material: Viton® Minimum layer thickness: 0,7 mm Break through time: 30 min Material tested:Vitoject® (KCL 890 / Aldrich Z677698, Size M)
Respiratory protection	Not required; except in case of aerosol formation.
Other Protection Measure	Handle in accordance with good industrial hygiene and safety practice.
Control of environmental exposure	Do not let product enter drains.

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Physical state	Liquid
Colour	Colorless
Odour	Characteristic, ester-like
Odor Threshold	No data available
pH	4,0 at 110 g/l at 20 °C
Melting Point	43 °C - lit.
Boiling Point	181 °C - lit.
Flash Point	73,5 °C
Evaporation Rate	Not Applicable
Flammability (solid, gas)	No data available
Explosive limits	No Data Available
Upper/lower flammability or explosive limits	9,5 %(V) 54 %(V) / 1,4 %(V)1,0 %(V)
Autoignition temperature	No data available
Decomposition temperature	No data available
Vapour pressure	0,26 hPa at 20 °C
Density	1,029 g/cm3 at 20 °C - lit.
Relative Density	1,03 at 20 °C
Vapour Density	4,49 - (Air = 1.0)
Relative vapor density	4,49 - (Air = 1.0)
Freezing point	No data available
Viscosity dynamic	1,696 mPa.s at 20 °C
Partition coefficient	log Pow: 0,8 at 20 °C
Explosive properties	No data available
Solubility	130,3 g/l at 20 °C
Ignition temperature	No information available.
Particle characteristics	No data available

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Reactivity	Forms explosive mixtures with air on intense heating. A range from approx. 15 Kelvin below the flash point is to be rated as critical.
Stability	The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions	Violent reactions possible with: Strong oxidizing agents Strong acids Strong bases
Conditions to avoid	Strong heating.
Incompatible materials	No data available
Hazardous decomposition products	In the event of fire: see section 5

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Acute toxicity	LD50 Oral - Rat - female - 10.800 mg/kg (OECD Test Guideline 401) LC50 Inhalation - Rabbit - male and female - 4 h - > 49,2 mg/l - vapor Remarks: (in analogy to similar products) (ECHA) The value is given in analogy to the following substances: methyl acetate Symptoms: Possible damages:, mucosal irritations LD50 Dermal - Rat - male and female - > 2.000 mg/kg (OECD Test Guideline 402)
Skin corrosion/irritation	Skin - Rabbit Result: No skin irritation - 4 h (OECD Test Guideline 404)
Serious eye damage/eye irritation	Eyes - Rabbit Result: No eye irritation - 24 h (OECD Test Guideline 405)
Respiratory or skin sensitization	Freund's complete adjuvant test - Guinea pig Result: negative (OECD Test Guideline 406)
Toxic Effects on Human	May cause damage to the following organs: upper respiratory tract. Other Toxic Effects on Humans: Hazardous in case of skin contact (irritant, sensitizer), of ingestion, of inhalation (lung irritant, lung sensitizer).
Carcinogenicity	No data available
Germ cell mutagenicity	Test Type: In vitro mammalian cell gene mutation test Test system: Chinese hamster lung cells Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 476 Result: negative Test Type: Ames test Test system: Escherichia coli/Salmonella typhimurium Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471 Result: negative
Reproductive toxicity	No data available
Specific target organ toxicity - single exposure	No data available
Special Remarks on other Toxi Effects on Humans	Acute Potential Health Effects: Skin: Causes skin irritation. May cause skin sensitization, an allergic reation, which becomes evident upon re-exposure to this material. Eyes: Causes eye irritation. Ingestion: Causes gastrointestinal (digestive) tract irritation with nausea, vomiting, and diarrhea. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May cause chemical pneumonitis and pulmonary edema, inflammation, edema of bronchi and larynx. Chronic Potential Health Effects: Repeated or prolonged skin exposure may cause allergic reactions in sensitive individuals. Repeated or prolonged exposure by inhalation may affect respiration and metabolism.
Endocrine disrupting properties	The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. Repeated dose toxicity - Rat - male and female - Oral - 28 d - NOAEL (No observed adverse effect level) - 1.000 mg/kg Remarks: Subacute toxicity No significant adverse effects were reported RTECS: AK5250000 To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. After absorption: Headache Dizziness Nausea Other dangerous properties can not be excluded. Handle in accordance with good industrial hygiene and safety practice.

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Bioaccumulative potential	No data available
Persistence and degradability	Biodegradability aerobic Chemical oxygen demand - Exposure time 28 d Result: 66 % - Readily biodegradable. (OECD Test Guideline 301D)
Toxicity to fish	Semi-static test LC50 - Danio rerio (zebra fish) - > 100 mg/l - 96 h (OECD Test Guideline 203)
Toxicity to daphnia and other aquatic invertebrates	Static test EC50 - Daphnia magna (Water flea) - > 100 mg/l - 48 h (OECD Test Guideline 202)
Toxicity to algae	Static test ErC50 - Desmodesmus subspicatus (green algae) - > 100 mg/l - 72 h (OECD Test Guideline 201)
Toxicity to bacteria	Static test EC50 - activated sludge - 563 mg/l - 3 h (OECD Test Guideline 209) Remarks: (in analogy to similar products) The value is given in analogy to the following substances: sodium hypochlorite solution
Mobility in soil	No Information available
Results of PBT and vPvB assessment	This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Endocrine disrupting properties	The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
Other adverse effects	Discharge into the environment must be avoided.

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Disposal methods	The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging	Dispose of as unused product.
Waste treatment Method	See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.

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UN number	ADR/RID: IMDG: IATA:
UN proper shipping name	ADR/RID: IMDG: IATA:
Transport hazard class(es)	ADR/RID: IMDG: IATA:
Packaging group	ADR/RID: IMDG: IATA:
Environmental hazards	ADR/RID: NO IMDG: NO IATA: NO
Further information	No data available

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Inventory status	Components are on the following inventories: Polymaleic acid: - US TSCA, Canadian DSL, EU EINECS, Australian AICS, Korean, Philippine PICCS and Chinese Xi irritant R 36/38 Irritant to eyes & skin R 41 Risk of serious damage to eyes S24/25 Avoid contact with skin and eyes S26/28 In case of contact eyes & skin, rinse with plenty water and seek medical advice Section 312/313: Not listed. Not listed under California proposition 65.
Safety, health and environmental regulations/legislation specific for the substance or mixture	This material safety data sheet complies with the requirements of Regulation (EC) No. 1907/2006.
National legislation	Seveso III: Directive 2012/18/EU of the European Parliament and of the Council on the control of major-accident hazards involving dangerous substances. : ACUTE TOXIC : ENVIRONMENTAL HAZARDS
Other regulations	Observe work restrictions regarding maternity protection in accordance to Dir 92/85/EEC or stricter national regulations where applicable. Take note of Dir 94/33/EC on the protection of young people at work.
Chemical Safety Assessment	For this product a chemical safety assessment was not carried out

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Other Information

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and weassume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Rx Marine International has been advised of the possibility of such damages.

DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable.